39 year female with fever

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 I have been given this case to solve in an attempt to understand the topic of " Patient clinical data analysis" to develop my competancy in reading and comprehending clinical data including history, clinical finding, investigations and come up with a  diagnosis and treatment plan

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The patient and the attenders have been adequately informed about this documentation and privacy of the patient is being entirely conserved. No identifiers shall be revealed through out the piece of work whatsoever



PRESENTING COMPLAINTS:
C/O Fever since 8 days.
C/O Generalized weakness for 6 days.
C/O SOB since a day.
C/O Loose stools for a day.

HOPI:
A 39 year female, Agriculturer by occupation clinically presented to casuality with complaints of High grade intermittent fever associated with chills and rigors, after a day she sought for consultation at a local RMP, she was started on IV fluids and sent home; On day 3 of fever she had severe frontal headache, for which she sought for consultation at local hospital and underwent treatment for typhoid fever for 5 days; during the course of hospital she still having high grade fever not associated with chills and rigors, generalized weakness for day 6 of fever; she was only on liquid diet during hospital stay. On day 7 of her fever she had an episode of loose stools, watery in consistency, non blood stained which was resolved on having medication and had shortness of breath of grade II NYHA for a day. The patient underwent routine work up, her Hb 8.6 gms%, TLC 11,600; Platelet 1.74lakhs/mm³; CRP 67 IU/L; WIDAL : O 1:160 ; H 1: 160 dilutions for S Typhi; Malaria test -ve; Dengue serology negative.
USG ABDOMEN done on 07/09/2022 showed findings s/o - Bilateral moderate pleural effusion; mild Ascites; Gall bladder wall edema. HRCT done on 07/09/2022 showed findings s/o - Bilateral Moderate pleural effusion; Atelectatic bands in bilateral lung fields predominantly in subpleural distribution; Moderate ascites. Patient and her attendee has been discharged as LAMA and sought for consultation and admitted now for further evaluation and management.

PAST ILLNESS:
No Comorbidities.

PERSONAL HISTORY:
Moderately built and nourished.
Appetite normal.
Decreased food intake because of nausea.
Bowel and bladder are regular.
Allergic to Dust.
No addictions.

FAMILY HISTORY:
No similar compalaints in the family.

MENSTRUAL HISTORY:
Age at Menarche: 15 yrs.
5/28 day cycle.
Menses were started on the day of admission at 5pm.

OBSTETRIC HISTORY:
Age at Marriage: 17 yrs.
Age at 1st child birth : 19 yrs.
1st pregnancy: male child; spontaneous; Full term normal vaginal delivery + Episiotomy.
2nd pregnancy: female child; spontaneous; Full term normal vaginal delivery.

GENERAL EXAMINATION:
Patient was conscious and coherent.
Afebrile; Temp : 98.4°F.
PR: 84bpm; BP: 110/80mmHg; RR: 19cpm; SpO2: 98%@RA; GRBS: 97mg/dl.
CVS: S1,S2+; R/S: BAE+, Bilateral crepts at IAA; P/A: Soft, Non tender, BS+; CNS: NFND.

COURSE IN THE HOSPITAL:
A 39 year female presented with above mentioned complaints. Necessary investigations were done. Initial assessment was done. No postural drop, her BP on supine position was 110/60mmHg and standing was 110/70mmHg. A fever spike with a temp of 104.6°F was recorded in casuality and started her on IV Antipyretic. She has been shifted to ICU and handed over to ICU team. Her BP was 70/50mmHg and initial fluid resuscitation was done but the bp was not maintained to support the MAP. She was started on IV NORAD Infusion @5ml/hour. Her BP was 90/60 mmHg and complaining of an episode of loose stools. Her Hb was 10.4gm%; TLC 12700; platelet 210000 cells cu.mm. PT 14 sec; APTT 28 sec & INR 1.0. She had a fever spike of 100.6°F at 4 AM; and had complaints of nausea. Improvement in generalized weakness. On examination she had decreased breath sounds on ausculation at bilateral IAA & ISA; and dullness notes on percussion at bilateral IAA & ISA. Her BP was 90/70 mmHg on NA@1ml/hr; RR 32 cpm.

She was de-esculated from NORAD after her BP and MAP are maintained. Blood for culture and sensitivity was negative for bacterial growth. Her pleural effusion and ascites was gradually resolved. She had complaints of loose stools after 4 days of admission and the antibiotics she was on were de-escalated; and started on Enterogermina liquid for 2 days. During the stay in hospital she was treated with IV Antipyretic, Analgesic, Antibiotic and other supportive medications. She was started ambulating. Her condition was gradually improved. She was being discharged in a hemodynamically stable condition.


ECG AT PRESENTATION:
CHEST XRAY PA VIEW:
On day of presentation:-

On day 3 of admission 
FEVER CHART:
INVESTIGATIONS CHART:
(OUTSIDE)
(NOW)
Clinical Images:
DIAGNOSIS:
VIRAL PYREXIA WITH POLYSEROSITIS;
SEPSIS RESOLVED 

TREATMENT:
1. IVF NS/RL @125ML/HOUR 
2. INJ. NORAD @3ML/ HOUR.
3. INJ. NEOMOL 100ML /IV/SOS (IF TEMP>101°F)
4. TAB. MONTAIR LC /PO/HS.
5. TAB. DOLO 650MG/PO/QID.

DISCHARGE MEDICATION:
1. PLENTY OF ORAL FLUIDS 
2. HIGH PROTEIN BALANCED DIET.
3. TAB. NAPROXEN 500mg ONCE DAILY AS ADVICED (IF HEADACHE)
4. TAB. MVT /PO/OD.


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